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Vicodin ES is a powerful narcotic pain reliever and muscle relaxer. It is used to treat moderate to severe pain. Vicodin ES is a combination of the opioid hydrocodone and the non-opioid analgesic acetaminophen. Hydrocodone works by changing the way the brain and nervous system respond to pain. Acetaminophen helps to reduce fever and also may increase the effects of hydrocodone.
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